Because you want to reduce the batch-to-batch variations inherent to the use of an
unstable and non reproducible component, such as Fetal Calf Serum
Because you want to prevent the risk of serum shortages & prion contaminations
Because you want to master / adapt the formulation of your culture medium
Example with Triple-Negative Breast Cancer cell line MDA-MB-231
From Dubois et al. J. Clinical Medicine (2019)
Example with Triple-Negative Breast Cancer cell line MDA-MB-231
From Dubois et al. J. Clinical Medicine (2019)
Living cells (green) and dead cells (red)